Endocrine Abstracts

Background: Ectopic Cushing Syndrom (ECS) represents approximately 12% of all patients with Cushing´s disease. Either ACTH (5–10%), CRH or cortisol is produced uncontrolled from nonpituitary tissue. Half of ECS cases are neuroendocrine lung tumors [carcinoid tumors > small cell lung carcinoma (SCLC)], but ECS is clinically apparent only in 1–5% of SCLC cases. Clinical features vary according to extent and duration of exposure to ACTH/Cortisol excess and in...